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6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-hal

Sharaxaad Gaaban:

Magaca kiimikada:6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-hal

CAS: 1256578-99-0

Kiimikada formula:C13H15Bro2

Miisaanka molecular: 283.16

Cufnaanta: 1.3 ± 0.1g/cm3

Barta karkarinta: 354.7 ± 42.0 ℃ (760 mmHg)

 


Faahfaahinta Alaabta

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Sharaxaada Alaabta

Dabeecadaha kiimikada

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-hal waa dareere hufan oo huruud ah oo aan midab lahayn ama iftiin ah, aan biyo lagu milmi karin, ku milma CHCl3Kaydinta waa in la qaboojiyaa, laga soocaa oksaydhiyeyaasha, kiimikooyinka la cuni karo, ka fog dabka, isha kulaylka.

Codsiyada

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-halwaa dhexdhexaadka Alectinib, oo ah mid aad u doora oo awood leh anaplastic lymphoma kinase (ALK) inhibitor oo awood u leh in uu xannibo mutant-ga ilaaliye u adkaysta, taas oo keenta hoos u dhaca koritaanka unugyada.

Qaab jireed

Dareere aan midab lahayn ama huruud ah

Nolosha shelf

Marka loo eego waayo-aragnimadayada, badeecada waxaa lagu kaydin karaa 12bilo laga bilaabo taariikhda dhalmada haddii lagu hayo weel si adag loo xidhay, laga ilaaliyo iftiinka iyo kulaylka laguna kaydiyo heerkul u dhexeeya 5 -30°C.

Tguryaha caadiga ah

Barta Karsan

354.7±42.0 °C at 760 mmHg

Barta Fiishka

168.3 ± 27.9 °C

Mass sax ah

282.025543

PSA

26.30000

LogP

3.25

Cadaadis uumiga

0.0±0.8 mmHg at 25°C

Tusmada Milicsiga

1.545

pka

1.26±0.10 (La saadaaliyay)

Biyuhu milmayn

50 mg/ml ee CHCl3

 

 

Badbaadada

Markaad gacanta ku hayso alaabtan, fadlan raac talada iyo macluumaadka lagu sheegay xaashida xogta badbaadada oo ilaali ilaalinta iyo tallaabooyinka nadaafadda goobta shaqada ee ku filan maaraynta kiimikooyinka.

 

Ogow

Xogta ku jirta daabacaadan waxay ku salaysan tahay aqoonta iyo waayo-aragnimadayada hadda.Iyadoo la eegayo arrimo badan oo saamayn kara habaynta iyo ku-dhaqanka alaabtayada, xogtani kama fududayso soo-saareyaasha inay sameeyaan baadhitaano iyo baadhitaano iyaga u gaar ah;Xogtaasi kama tarjumeyso wax dammaanad qaad ah oo ah hanti gaar ah, ama ku habboonaanta alaabta ujeeddo gaar ah.Sharaxaad kasta, sawiro, sawiro, xog, saamiyo, miisaan, iwm. halkan lagu bixiyay waxa laga yaabaa inay isbedesho iyada oo aan xog hore laga hayn oo ma aha tayada qandaraaska ee la isku raacay.Tayada qandaraaska ee lagu heshiiyey ee badeecada ayaa si gaar ah uga soo baxda bayaanka lagu sheegay qeexida alaabta.Waa mas'uuliyadda qaataha alaabtayada si loo hubiyo in la ilaaliyo xuquuq kasta oo lahaanshaha iyo sharciyada jira iyo sharciga.


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